Set just off the iconic DePortola Wine Trail, 20 Calle Las Lomas presents a rare opportunity to own 20 acres in the heart of Temecula Wine Country. Surrounded by premier wineries, luxury estate properties, and open vineyard landscapes, this expansive parcel offers an exceptional balance of privacy, accessibility, and long-term potential. Zoned RA-10 and positioned within the Wine Country Equestrian district, the land is defined by gently rolling to level terrain, multiple flat building pads suitable for a variety of structures, and sweeping panoramic views across the Temecula Valley, surrounding vineyards, and distant mountain ranges. Multiple natural building areas provide flexibility for a variety of visions, from a legacy estate compound to a vineyard-focused retreat or boutique hospitality concept. The setting is peaceful and expansive, yet only minutes from town conveniences, dining, and shopping. Infrastructure is already in place with water available at the street, one installed meter, power nearby, and established road access, creating a meaningful advantage for future development. The parcel offers the potential to subdivide into two ten-acre lots, further enhancing flexibility for investment or phased development strategies. Located moments from renowned wineries including Renzoni, Leoness, Oak Mountain, Altisima, Fazeli, and Somerset, and near the 7,000-acre Vail Lake Reserve, the area is a destination for wine tourism, outdoor recreation, and refined countryside living. Opportunities of this scale, usability, and location are increasingly rare in Temecula Wine Country. Whether envisioned as a private estate, winery project, or long-term land investment, 20 Calle Las Lomas offers a compelling canvas in one of Southern California's most sought-after lifestyle regions.